Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 15mg | ||||
180 pill | 15mg | $1,061.99 | $5.90 | |
120 pill | 15mg | $719.99 | $6.00 | |
90 pill | 15mg | $548.99 | $6.10 | |
60 pill | 15mg | $371.99 | $6.20 | |
30 pill | 15mg | $188.99 | $6.30 | |
20 pill | 15mg | $127.99 | $6.40 | |
10 pill | 15mg | $64.99 | $6.50 | |
Dosage: 30mg | ||||
120 pill | 30mg | $937.99 | $7.82 | |
90 pill | 30mg | $715.99 | $7.96 | |
60 pill | 30mg | $485.99 | $8.10 | |
30 pill | 30mg | $244.99 | $8.17 | |
20 pill | 30mg | $164.99 | $8.25 | |
10 pill | 30mg | $82.99 | $8.30 |

Tolvaptan Description
Introduction to Tolvaptan
Tolvaptan is an oral medication primarily used to treat conditions related to fluid retention and water imbalance. It belongs to a class of drugs known as vasopressin receptor antagonists. The medication works by blocking the activity of vasopressin, a hormone that regulates water reabsorption in the kidneys. By inhibiting vasopressin, Tolvaptan promotes the excretion of free water without significant loss of electrolytes, helping to correct hyponatremia and reduce excessive fluid buildup.
Uses and Medical Benefits
This medication is often prescribed for the treatment of hyponatremia, especially in cases where low sodium levels are caused by conditions such as syndrome of inappropriate antidiuretic hormone secretion (SIADH). It’s also used in patients with autosomal dominant polycystic kidney disease (ADPKD) to slow disease progression and preserve kidney function. In such cases, Tolvaptan helps reduce the growth of kidney cysts, which can lead to improved long-term health outcomes. Its ability to carefully manage water levels makes it a valuable tool in maintaining electrolyte balance and preventing complications associated with fluid overload.
Administration and Dosage
Tolvaptan is typically taken once or twice daily, with dosing depending on the condition being treated and the patient's response. It’s important to follow the prescribing doctor’s instructions precisely. The medication is usually taken with water, and patients are advised to maintain adequate hydration. Because the drug can significantly alter water and electrolyte balances, regular monitoring of serum sodium levels is necessary during treatment. Adjustments to dosage may be required based on test results and clinical response.
Potential Side Effects and Risks
Like all medications, Tolvaptan can cause side effects. Common adverse reactions include thirst, dry mouth, increased urination, and headache. Some patients may experience gastrointestinal symptoms such as nausea or diarrhea. More serious but less common risks involve rapid correction of sodium levels, which can lead to a condition called osmotic demyelination syndrome, a potentially life-threatening neurological disorder. Liver toxicity is another concern, especially with long-term use, so liver function tests are often recommended during therapy. Patients should report any symptoms of liver issues, such as jaundice, fatigue, or abdominal pain, promptly.
Precautions and Interactions
Before starting Tolvaptan, patients should inform their healthcare provider about all other medications they are taking. Certain drugs, particularly those affecting electrolyte balance or kidney function, may interact with Tolvaptan and influence its effectiveness or safety. Caution is advised in patients with liver impairment, as the drug can exacerbate liver issues. It is also important to avoid alcohol while on this medication, as it can increase the risk of side effects and impair judgment. Regular medical checkups are vital to ensure the medication’s benefits outweigh any potential risks.
Conclusion
Overall, Tolvaptan is a valuable medication for managing specific water imbalance conditions and slowing the progression of polycystic kidney disease. Its targeted mechanism allows for precise water regulation, making it an effective choice for appropriate patients. However, due to its potential side effects and the necessity for careful monitoring, it should always be used under strict medical supervision. When prescribed correctly, Tolvaptan can significantly improve the quality of life for individuals facing these health challenges, making it an important option in modern treatment protocols.