Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 25mg | ||||
120 pill | 25mg | $108.99 | $0.91 | |
90 pill | 25mg | $85.99 | $0.95 | |
60 pill | 25mg | $58.99 | $0.98 | |
30 pill | 25mg | $30.99 | $1.04 | |
Dosage: 50mg | ||||
270 pill | 50mg | $239.99 | $0.89 | |
240 pill | 50mg | $217.99 | $0.91 | |
120 pill | 50mg | $127.99 | $1.07 | |
90 pill | 50mg | $111.99 | $1.24 | |
60 pill | 50mg | $77.99 | $1.30 | |
30 pill | 50mg | $40.99 | $1.36 |

Azathioprine Description
Overview of Azathioprine
Azathioprine is an immunosuppressive medication commonly prescribed to prevent organ rejection after transplantation and to treat certain autoimmune diseases. It works by suppressing the immune system’s activity, reducing inflammation and immune responses that can damage tissues. This medication has been used for decades, and it is well-known for its effectiveness in managing complex medical conditions. Patients often rely on Azathioprine to maintain remission in diseases like rheumatoid arthritis, Crohn’s disease, and ulcerative colitis. When used appropriately, it can significantly improve quality of life and prevent serious complications associated with autoimmune responses.
How Azathioprine Works
Azathioprine is a prodrug, meaning it is converted inside the body into active metabolites. The primary mechanism involves inhibiting the synthesis of purines, which are essential components of DNA and RNA. By interfering with these building blocks, Azathioprine effectively reduces the proliferation of overactive immune cells. This suppression of immune function helps to decrease the inflammation and tissue damage caused by autoimmune diseases. However, because it modulates the immune response, patients taking Azathioprine need regular monitoring to avoid excessive immune suppression, which can increase the risk of infections.
Usage and Dosage
This medication is typically prescribed in tablet form. The dosage varies depending on the condition being treated, the patient’s weight, age, and response to therapy. Doctors usually start with a low dose, gradually increasing it to minimize side effects and improve tolerability. It’s important for patients to follow the prescribed schedule closely. Regular blood tests are necessary to monitor blood cell counts and liver function, as these can be affected by Azathioprine. Patients should never adjust their dose without consulting a healthcare provider. Consistent adherence to therapy and monitoring ensures safety and maximum effectiveness of the medication.
Potential Side Effects and Precautions
Like all medications, Azathioprine can cause side effects. Some common adverse effects include nausea, vomiting, and decreased appetite. More serious risks involve bone marrow suppression, leading to lowered blood counts that may cause anemia, increased bleeding risk, or susceptibility to infections. Patients may also experience liver toxicity, indicated by abnormal liver function tests. Because of these risks, regular laboratory tests are essential during treatment. Patients should inform their doctors about any signs of infection, unusual bleeding, or jaundice. Pregnant women or those planning to conceive should discuss potential risks, as Azathioprine can affect fetal development. Using reliable contraception during treatment is recommended.
Benefits and Efficacy
Despite its potential side effects, Azathioprine remains a cornerstone in the management of several autoimmune conditions. It effectively reduces disease activity and flares, helping patients maintain remission longer. Its ability to suppress immune responses means it can decrease the need for corticosteroids, which have their own significant side effects. Many patients experience improved quality of life with Azathioprine when used as part of a comprehensive treatment plan, including other medications and lifestyle modifications. Over the years, it has proven to be a valuable tool in controlling chronic autoimmune diseases and preventing organ rejection in transplant recipients.