Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 15mg | ||||
180 pill | 15mg | $1,061.99 | $5.90 | |
120 pill | 15mg | $719.99 | $6.00 | |
90 pill | 15mg | $548.99 | $6.10 | |
60 pill | 15mg | $371.99 | $6.20 | |
30 pill | 15mg | $188.99 | $6.30 | |
20 pill | 15mg | $127.99 | $6.40 | |
10 pill | 15mg | $64.99 | $6.50 | |
Dosage: 30mg | ||||
120 pill | 30mg | $937.99 | $7.82 | |
90 pill | 30mg | $715.99 | $7.96 | |
60 pill | 30mg | $485.99 | $8.10 | |
30 pill | 30mg | $244.99 | $8.17 | |
20 pill | 30mg | $164.99 | $8.25 | |
10 pill | 30mg | $82.99 | $8.30 |

Samsca Description
Overview of Samsca
Samsca, known generically as tolvaptan, is a prescription medication primarily used in the United States to treat specific types of the syndrome of inappropriate antidiuretic hormone secretion (SIADH). It functions by blocking the action of vasopressin, a hormone that regulates water retention in the body. By inhibiting vasopressin, Samsca helps increase water excretion without losing essential electrolytes, thereby reducing fluid buildup in patients. It is considered an important option for managing hyponatremia, a condition characterized by low sodium levels in the blood, which can be dangerous if left untreated.
How Does It Work?
The medication works by selectively antagonizing the vasopressin V2 receptors in the kidneys. This action prevents water reabsorption, leading to increased urine production and a correction of serum sodium levels. Unlike some diuretics, Samsca does not cause significant electrolyte imbalance, making it a safer choice for individuals with hyponatremia related to SIADH. Proper monitoring of sodium levels is essential when taking this medication to prevent overly rapid correction, which can lead to serious health risks.
Usage and Dosage
In the United States, Samsca is typically prescribed by healthcare professionals after careful assessment of the patient's condition. The usual starting dose is often 15 mg once daily, which can be adjusted based on the patient's response and serum sodium levels. For many patients, the maximum dose is 60 mg per day. It is important to follow the prescribing doctor’s instructions precisely. This medication is usually taken with water, and patients are advised to maintain adequate fluid intake as recommended by their healthcare provider.
Review of Effectiveness
Many patients in the USA report that Samsca effectively manages their hyponatremia, leading to improved symptoms and better quality of life. Healthcare providers often see quick improvements in sodium levels, especially when the medication is used alongside other treatments and with proper monitoring. However, some patients might experience fluctuations in sodium levels if not closely watched, underscoring the importance of regular blood tests during therapy. Overall, Samsca is regarded as a significant advancement in the treatment of certain fluid and electrolyte disorders.
Possible Side Effects and Precautions
Like all medications, Samsca can cause side effects. Commonly reported issues include thirst, dry mouth, and increased urination. Some individuals may also experience headaches, dizziness, or gastrointestinal discomfort. Serious side effects, although rare, can involve rapid changes in sodium levels leading to neurological symptoms like confusion, seizures, and coma. It is crucial to adhere to medical guidance on fluid intake and to undergo regular blood sodium checkups. Patients with liver disease or those taking other medications should inform their healthcare provider before starting Samsca, as it may have specific interactions or contraindications.
Availability and Purchase in the USA
In the United States, Samsca is available by prescription through licensed pharmacies. It is often obtained via online pharmacies that are accredited and compliant with federal and state regulations. Buyers should ensure they have a valid prescription and buy only from reputable sources to guarantee the medication's safety and authenticity. Consulting a healthcare professional before purchasing or starting treatment ensures that Samsca is suitable for your condition and that appropriate monitoring measures are in place.